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From Chapter 1:
"'It requires no effort of the fancy to picture these three men [Shakespeare, Bacon and Raleigh] as lounging in a window of Durham House, puffing the new Indian weed from silver bowls, discussing the highest themes in poetry and science, while gazing on the flower-beds and the river, the darting barges of dame and cavalier, and the distant pavilions of Paris garden and the Globe.'" This is a pure "effort of the fancy" so far as Bacon and Shakespeare are concerned. Shakespeare's absolute silence about tobacco forbids us to assume that he smoked; but of Raleigh the picture may be true enough. The house had, as Aubrey tells us, "a little turret that looked into and over the Thames, and had the prospect which is as pleasant perhaps as any in the world"; and it would be strange indeed if the owner of the noble house did not often smoke a contemplative pipe in the window of that pleasant turret.

From Chapter 7:
The satirist wrote truly that after all the fashionable abstainers had been deducted, crowds remained, who smoked as heartily as their predecessors of a century earlier. The populace was still on the side of tobacco. This was well shown in 1732 when Sir Robert Walpole proposed special excise duties on tobacco, and brought a Bill into Parliament which would have given his excisemen powers of inquisition which were much resented by the people generally. The controversy produced a host of squibs and caricatures, most of which were directed against the measure. The Bill was defeated in 1733, and great and general were the rejoicings. When the news reached Derby on April 19 in that year, the dealers in tobacco caused all the bells in the Derby churches to be rung, and we may be sure that this rather unusual performance was highly popular. The withdrawal of the odious duty was further celebrated by caricatures and "poetical" chants of triumph. One of the leading opponents of the Bill had been a well-known puffing tobacconist named Bradley, who was accustomed to describe his wares as "the best in Christendom"; and when the Bill was defeated Bradley's portrait was published for popular circulation, above these lines:

Behold the man, who, when a gloomy band
Of vile excisemen threatened all the land,
Help'd to deliver from their harpy gripe
The cheerful bottle and the social pipe.
O rare Ben Bradley! may for this the bowl,
Still unexcised, rejoice thy honest soul!
May still the best in Christendom for this
Cleave to thy stopper, and compleat thy bliss!